Biochemical HCG Structure

Belonging to the glycoprotein hormone family, HCG is a peptide hormone produced by trophoblast tissue at extremely high concentrations. HCG is made up of two subunits (α and β) that are not covalently connected. The β-subunit is specialized for HCG and has 145 amino acids, whereas the α-subunit has 95 amino acids and is also a component of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). The glycosylation variation of HCG known as hyperglycosylated HCG is generated by extravillous and root cytotrophoblast cells.

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