All RNA that can be transcribed by a particular cell in a certain functional state is the subject of whole transcriptome sequencing study, primarily mRNA and non-coding RNA like lncRNA and circRNA. Exosomes transport vital components from the parent cell, including short- and long-chain RNA, lipids, and a range of proteins. Comprehensive transcriptome sequencing and long-chain RNA analysis in exosomes can identify the distinct biomarkers that exosomes carry and are crucial for comprehending the internal workings of various developmental stages or disorders.
The entire transcriptome sequencing method for exosomes, developed by Creative Biolabs, fully integrates NGS technology, a novel biological information sequence comparison algorithm, and patented micro nucleic acid library creation technology. CircRNA and other RNAs are thoroughly sequenced to provide complete exosomal transcriptome data.
